Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation

The objective of this study was to investigate the antibacterial activity and potential mechanism alkyl gallates against Escherichia coli Staphylococcus aureus. Results show that length chain plays a pivotal role in eliciting octyl gallate (OG) exerted excellent bactericidal through multiple mechanism. OG functions both bacteria damaging bacterial cell wall integrity, permeating into cells then interacting with DNA, as well disturbing respiratory electron transport induce high-level toxic ROS (hydroxyl radicals) generation up-regulation genes. Also, electrospun nanofibers have unique superiorities for maintaining freshness icefish (4 °C). This research not only provides more in-depth understanding interaction between microorganisms but also highlights great promise using safe multi-functionalized food additive preservations.